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Surgeons painlessly operated under ether for the first time in public

On this day · 16 October 1846
40 sec read

In a Boston amphitheater, a patient slept through surgery as ether vapor banished pain and rewrote what an operation could be.

Verified · Massachusetts General Hospital Museum

On 16 October 1846, in the surgical amphitheater of Massachusetts General Hospital — now known as the Ether Dome — a Boston dentist named William T. G. Morton administered sulfuric ether to a patient before a crowd of skeptical physicians. As the man breathed vapor from a soaked sponge, surgeon John Collins Warren cut into his neck to remove a tumor.

The patient, housepainter Edward Gilbert Abbott, lay motionless and felt no pain. Turning to the watching doctors, Warren reportedly declared:

“Gentlemen, this is no humbug.”

Until that morning, surgery meant being held down and enduring agony fully awake. The public proof that inhaled anesthesia could erase that pain spread within weeks across America and Europe, transforming the operating room. The day is widely marked as the birth of modern anesthesiology.

1846
the year pain left surgery
3-inch
incision Abbott slept through

Sources & references

2 references

Well-established. Corroborated by 2 independent sources.

1 Massachusetts General Hospital Museum hospital museum “William T.G. Morton made history on October 16, 1846 in Massachusetts General Hospital's surgical amphitheater, now known as the Ether Dome, when he demonstrated the first public surgery using anesthetic (ether).” massgeneral.org ↗
2 Linda Hall Library article “Dr. John Collins Warren removed a tumor from the neck of Boston housepainter Edward Gilbert Abbott. Throughout the procedure, Abbott inhaled vapors from a sponge soaked in sulfuric ether, which were administered by a local dentist named William Morton.” lindahall.org ↗
✓ Last reviewed Jun 7, 2026

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