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◆ Nature & Animals · Marine Life

The "immortal jellyfish" can rewind its own life cycle

45 sec read

When stressed, this tiny jellyfish doesn't die — it reverts to a juvenile and starts over.

Verified · Menéndez et al., Scientific Reports — The Global Flood Protection Benefits of Mangroves

Most animals run their life cycle one way: birth, maturity, death. Turritopsis dohrnii, a jellyfish barely 4.5 millimetres across, can run it backwards.

When the adult medusa is injured, starved, or hit by a sudden change in temperature or salinity, it can collapse into a blob, settle to the seafloor, and grow back into a polyp — the immature colonial stage it came from. The reborn colony then buds off new, genetically identical medusae.

The trick is transdifferentiation: already-specialised cells switch directly into completely different cell types, effectively resetting the body’s clock. In the lab this reprogramming can happen in about 24 hours.

Because the cycle can repeat indefinitely, the animal is described as biologically immortal.

It is not truly deathless — predators and disease still kill it constantly — but its cellular reset makes it a prized model for research into ageing and regeneration.

4.5 mm
Maximum bell diameter
~24 hrs
Lab reset time

Sources & references

2 references

Well-established. Corroborated by 2 independent sources.

1 Menéndez et al., Scientific Reports — The Global Flood Protection Benefits of Mangroves academic “Medusae respond to damage or senescence by metamorphosing into a juvenile stage (the polyp); the medusa naturally undergoes cellular reprogramming to revert to a younger life cycle stage, thus avoiding death indefinitely, in approximately 24 h.” ncbi.nlm.nih.gov ↗
2 Wikipedia Community encyclopedia “All stages of the medusae can transform back into polyps under starvation, sudden temperature change, reduction of salinity, and artificial damage; the medusa is about 4.5 mm in diameter, and the process renders the jellyfish biologically immortal through transdifferentiation.” en.wikipedia.org ↗
✓ Last reviewed Jun 6, 2026

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